Fruit of the Loom has had some really terrific ad campaigns over the last few years. This one about appropriate underwear gift-giving cracked me up with its poignancy when it first hit the small screen a couple years back. (Raise your hand if you're a married, 30-something woman whose mother still gives you undies at Christmas.) (Hi, Mom.)
More recently, this ad makes me laugh every time it pops up. The thing with clever marketing is that if it doesn't help you remember the brand or product, what's the point? Fruit of the Loom nails it because they manage to be funny, memorable, and brand-appropriate while highlighting the features of the product. No easy feat for many brands, but particularly impressive when marketing unmentionables.
Bonus: these aren't bad, either.